Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43
Godoy-Corchuelo, J. M., Ali, Z., Brito Armas, J. M., Martins-Bach, A. B., García-Toledo, I., Fernández-Beltrán, L. C., López-Carbonero, J. I., Bascuñana, P., Spring, S., Jimenez-Coca, I., Muñoz de Bustillo Alfaro, R. A., Sánchez-Barrena, M. J., Nair, R. R., Nieman, B. J., Lerch, J. P., Miller, K. L., Ozdinler, H. P., Fisher, E. M. C., Cunningham, T. J., Acevedo-Arozena, A., Corrochano, S.
Pleiotropic brain function of whirlin identified by a novel mutation
Aguilar, C., Williams, D., Kurapati, R., Bains, R. S., Mburu, P., Parker, A., Williams, J., Concas, D., Tateossian, H., Haynes, A. R., Banks, G., Vikhe, P., Heise, I., Hutchison, M., Atkins, G., Gillard, S., Starbuck, B., Oliveri, S., Blake, A., Sethi, S., Kumar, S., Bardhan, T., Jeng, J. Y., Johnson, S. L., Corns, L. F., Marcotti, W., Simon, M., Wells, S., Potter, P. K., Lad, H. V.
PKD1L1 Is Involved in Congenital Chylothorax
Whitchurch, J. B., Schneider, S., Hilger, A. C., Köllges, R., Stegmann, J. D., Waffenschmidt, L., Dyer, L., Thiele, H., Dhabhai, B., Dakal, T. C., Müller, A., Norris, D. P., Reutter, H. M.
Neuroinflammation and Lysosomal Abnormalities Characterise the Essential Role for Oxidation Resistance 1 in the Developing and Adult Cerebellum
Bucknor, E. M. V., Johnson, E., Efthymiou, S., Alvi, J. R., Sultan, T., Houlden, H., Maroofian, R., Karimiani, E. G., Finelli, M. J., Oliver, P. L.
Naturally sterile Mus spretus hybrids are suitable for the generation of pseudopregnant embryo transfer recipients
Preece, C., Biggs, D., Grencis, E., Jackson, M. S., Allen, S., Fray, M., Adamson, A., Davies, B.