The MRC Harwell Institute’s website has been archived


The old website can now be found on the National Archives database where it will be stored to maintain an accurate record of its historical significance.

A high quality service from experimental design to data generation.

At the Mary Lyon Centre at MRC Harwell, we are working to improve our understanding of human disease through the study of mouse models and providing mouse genetics services to scientists around the world. These services cover all aspects of preclinical disease modelling in mice, including mouse model generation, a wide array of phenotyping tests, and archiving and distribution services. We adhere to the highest welfare standards and are proactively committed to implementing the 3Rs for the benefit of mouse health and welfare, while also improving the quality of the scientific data generated.

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Enabling mouse genetics research for academia and industry

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Professional, responsive, and able to keep up with ever-changing demand and tight deadlines. When it comes to mouse research, you'll definitely get the 5-star treatment from the Mary Lyon Centre
- Cryopreservation of mouse sperm service

Advance is a purpose built, high-quality, scientific training centre

Advance will build on MRC Harwell’s strong reputation for providing engaging training courses in mouse genetics, genome editing, pathology, and cryopreservation. Dedicated to improving health and plays a leading role in training future research leaders across a range of biomedical, clinical and health disciplines.

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Free bespoke mouse models with GEMM

Submit an application to our yearly GEMM programme which allows researchers to apply for a freely generated mouse line by the Mary Lyon Centre. GEMM offers a comprehensive genome engineering service that can meet researchers’ specific requirements.

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Catch up on the latest news to come out of the Mary Lyon Centre

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5 April 2022

A celebration of the MRC Mammalian Genetics Unit

On Friday 18th March, we hosted an event to mark the closure of the MRC Mammalian Genetics Unit (MGU) and,…

28 March 2022

Celebrating the skills, talents, experience, and dedication of technicians

Louisa Zolkiewski wins the 2021 Weilin Wang Prize

30 November 2021

Humanising mice to enable modelling of neurodegenerative diseases

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