The Bioinformatics of Mutant Mouse Resources – A two-day hands-on introduction Mouse Genetics 2011 conference Washington, DC (26th and 27th June 2011) In association with the Mouse Genetics 2011 conference, the Wellcome Trust Sanger Institute and MRC Harwell, we are pleased to announce a two day workshop “The Bioinformatics of Mutant Mouse Resources”. Each participant will be required to provide their own wireless enabled laptop for the duration of the course. At the end of this training, participants will be able to find their favourite genes, understand their gene structures in detail, as well as the underlying experimental data supporting the annotation. They will gain basic understanding and usability of comparative genomics and be able to observe the synteny surrounding their regions of study. They will also be introduced to non-specialist data mining skills. Participants will be able to find mutant mouse resources for their genes of interest using the IKMC (International Knockout Mouse Consortium) and similar resources. They will gain basic understanding of the different alleles available from various pipelines, identifying their strengths and weaknesses for different applications. They will be able to judge the quality of the KO strategies offered, draw their own vector maps and find key elements for the targeting strategy and genotyping. Participants will be able to search IMPC (International Mouse Phenotype Consortium) phenotypic databases of IKMC mouse mutants such as EuroPhenome, gain an understanding of the high-throughput phenotype data generated and the statistical approaches required to analyse it. They will also be able to compare and interpret this data with other phenotype data sources and identify mouse models of relevance to their clinical domain of interest. This course is limited to 40 participants and will be held in English. The course manual will be made available as a PDF and will be sent out to participants one week prior to the course, and will also be available online during the workshop. Please visit the registration page for further details. Ensure you select the ‘Satellite workshop on Bioinformatics of mutant mouse resources’ in the Optional Events section of the registration form. There will be a course fee of $150 for all participants. Participants will be expected to arrange and fund their own travel and accommodation.
