The Mary Lyon Centre (MLC) at MRC Harwell has been chosen to house the Wellcome Trust Sanger Institute’s Bio-Archive as part of the process that will lead to the closure of the Institute’s animal research facilities in September 2021. This extensive sample archive contains paraffin embedded tissues from the International Mouse Phenotyping Consortium (IMPC) and Sanger’s own mouse lines as well as plasma samples from some of the lines. The MLC has extensive experience curating archived collections as it holds and distributes samples from several other mouse and primate tissue archives. This wealth of biological material allows the scientific community to access existing and novel models which have been developed at Harwell and other institutes.
The MLC is a national facility providing world-class expertise, tools and resources to generate and characterise genetically altered mouse models for use by clinical and biomedical scientists. MLC resources support academic researchers throughout the UK and include genome engineering, advanced phenotyping and cryopreservation. All services are underpinned by quality-controlled husbandry and animal care with an emphasis on refinement and reproducibility.
If you are interested in acquiring any further information on the services provided by the MLC please view our Resources