Consortium Papers

Publications detailing the collaborative efforts of the MLC with international consortia involved in the targeted construction and phenotyping of mutant mouse lines, as well as the archiving and distribution of mouse disease models and disease gene discovery. These include the IMPC, EUMODIC and INFRAFRONTIER.

Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice

Oestereicher, M. A., Wotton, J. M., Ayabe, S., Bou About, G., Cheng, T. K., Choi, J. H., Clary, D., Dew, E. M., Elfertak, L., Guimond, A., Haseli Mashhadi, H., Heaney, J. D., Kelsey, L., Keskivali-Bond, P., Lopez Gomez, F., Marschall, S., McFarland, M., Meziane, H., Munoz Fuentes, V., Nam, K. H., Nichtová, Z., Pimm, D., Bower, L., Prochazka, J., Rozman, J., Santos, L., Stewart, M., Tanaka, N., Ward, C. S., Willett, A. M. E., Wilson, R., Braun, R. E., Dickinson, M. E., Flenniken, A. M., Herault, Y., Lloyd, K. C. K., Mallon, A. M., McKerlie, C., Murray, S. A., Nutter, L. M. J., Sedlacek, R., Seong, J. K., Sorg, T., Tamura, M., Wells, S., Schneltzer, E., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., White, J. K., Spielmann, N.

(2023) , Mamm Genome , 34 , 180-199

10.1007/s00335-023-09995-y

37294348

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Mendelian gene identification through mouse embryo viability screening

Cacheiro, P., Westerberg, C. H., Mager, J., Dickinson, M. E., Nutter, L. M. J., Muñoz-Fuentes, V., Hsu, C. W., Van den Veyver, I. B., Flenniken, A. M., McKerlie, C., Murray, S. A., Teboul, L., Heaney, J. D., Lloyd, K. C. K., Lanoue, L., Braun, R. E., White, J. K., Creighton, A. K., Laurin, V., Guo, R., Qu, D., Wells, S., Cleak, J., Bunton-Stasyshyn, R., Stewart, M., Harrisson, J., Mason, J., Haseli Mashhadi, H., Parkinson, H., Mallon, A. M., Smedley, D.

(2022) , Genome Med , 14 , 119

10.1186/s13073-022-01118-7

PMC9563108

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Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

Spielmann, S, Miller, G., Oprea, T.I., et al.

(2022) , Nat Cardiovasc Res , 1 , 157-173

10.1038/s44161-022-00018-8

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Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes

Higgins, K., Moore, B. A., Berberovic, Z., Adissu, H. A., Eskandarian, M., Flenniken, A. M., Shao, A., Imai, D. M., Clary, D., Lanoue, L., Newbigging, S., Nutter, L. M. J., Adams, D. J., Bosch, F., Braun, R. E., Brown, S. D. M., Dickinson, M. E., Dobbie, M., Flicek, P., Gao, X., Galande, S., Grobler, A., Heaney, J. D., Herault, Y., de Angelis, M. H., Chin, H. G., Mammano, F., Qin, C., Shiroishi, T., Sedlacek, R., Seong, J. K., Xu, Y., Lloyd, K. C. K., McKerlie, C., Moshiri, A.

(2022) , Sci Rep , 12 , 20791

10.1038/s41598-022-19710-7

PMC9715561

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A resource of targeted mutant mouse lines for 5,061 genes

Birling, M. C., Yoshiki, A., Adams, D. J., Ayabe, S., Beaudet, A. L., Bottomley, J., Bradley, A., Brown, S. D. M., Bürger, A., Bushell, W., Chiani, F., Chin, H. G., Christou, S., Codner, G. F., DeMayo, F. J., Dickinson, M. E., Doe, B., Donahue, L. R., Fray, M. D., Gambadoro, A., Gao, X., Gertsenstein, M., Gomez-Segura, A., Goodwin, L. O., Heaney, J. D., Hérault, Y., de Angelis, M. H., Jiang, S. T., Justice, M. J., Kasparek, P., King, R. E., Kühn, R., Lee, H., Lee, Y. J., Liu, Z., Lloyd, K. C. K., Lorenzo, I., Mallon, A. M., McKerlie, C., Meehan, T. F., Fuentes, V. M., Newman, S., Nutter, L. M. J., Oh, G. T., Pavlovic, G., Ramirez-Solis, R., Rosen, B., Ryder, E. J., Santos, L. A., Schick, J., Seavitt, J. R., Sedlacek, R., Seisenberger, C., Seong, J. K., Skarnes, W. C., Sorg, T., Steel, K. P., Tamura, M., Tocchini-Valentini, G. P., Wang, C. L., Wardle-Jones, H., Wattenhofer-Donzé, M., Wells, S., Wiles, M. V., Willis, B. J., Wood, J. A., Wurst, W., Xu, Y., Teboul, L., Murray, S. A.

(2021) , Nat Genet , 53 , 416-419

10.1038/s41588-021-00825-y

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