Guidelines and Commentaries

We publish guidelines in areas of relevance to our community, such as mouse pathology, high-throughput phenotyping, and screening and validation of genome-edited animals, as well as commentaries on the latest issues of interest.

Recommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal research

Lucas, R. J., Allen, A. E., Brainard, G. C., Brown, T. M., Dauchy, R. T., Didikoglu, A., Do, M. T. H., Gaskill, B. N., Hattar, S., Hawkins, P., Hut, R. A., McDowell, R. J., Nelson, R. J., Prins, J. B., Schmidt, T. M., Takahashi, J. S., Verma, V., Voikar, V., Wells, S., Peirson, S. N.

(2024) , PLoS Biol , 22 , e3002535

10.1371/journal.pbio.3002535

PMC10931507

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Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)

Ellwanger, K., Brill, J. A., de Boer, E., Efthymiou, S., Elgersma, Y., Icmat, M., Lecoquierre, F., Lobato, A. G., Morleo, M., Ori, M., Schaffer, A. E., Vitobello, A., Wells, S., Yalcin, B., Zhai, R. G., Sturm, M., Zurek, B., Graessner, H., Bermejo-Sánchez, E., Evangelista, T., Hoogerbrugge, N., Nigro, V., Schüle, R., Verloes, A., Brunner, H., Campeau, P. M., Lasko, P., Riess, O.

(2024) , Lab Anim , 53 , 161-165

10.1038/s41684-024-01395-2

PMC11216991

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Improving laboratory animal genetic reporting: LAG-R guidelines

Teboul, L., Amos-Landgraf, J., Benavides, F. J., Birling, M. C., Brown, S. D. M., Bryda, E., Bunton-Stasyshyn, R., Chin, H. J., Crispo, M., Delerue, F., Dobbie, M., Franklin, C. L., Fuchtbauer, E. M., Gao, X., Golzio, C., Haffner, R., Hérault, Y., Hrabe de Angelis, M., Lloyd, K. C. K., Magnuson, T. R., Montoliu, L., Murray, S. A., Nam, K. H., Nutter, L. M. J., Pailhoux, E., Pardo Manuel de Villena, F., Peterson, K., Reinholdt, L., Sedlacek, R., Seong, J. K., Shiroishi, T., Smith, C., Takeo, T., Tinsley, L., Vilotte, J. L., Warming, S., Wells, S., Whitelaw, C. B., Yoshiki, A., Asian Mouse Mutagenesis Resource Assocation, CELPHEDIA infrastructure, INFRAFRONTIER consortium, International Mammalian Genome Society, International Mouse Phenotyping Consortium, International Society for Transgenic Technologies, Mutant Mouse Resource and Research Centers, Phenomics Australia, RRRC- Rat Resource and Research Center, Pavlovic, G.

(2024) , Nat Commun , 15 , 5574

10.1038/s41467-024-49439-y

PMC11220107

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Implementing Quality Systems in the Management of the Animal Care and Use Program

Guillén, J., Kalman, R., Wells, S., Gardiner, M., Steckler, T.

(2024) , In "Practical Managment of Research Animal Care and Use Programs" , , 357-372

10.1007/978-3-031-65414-5_18

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Beyond genomic studies of congenital heart defects through systematic modelling and phenotyping

Henderson, D. J., Alqahtani, A., Chaudhry, B., Cook, A., Eley, L., Houyel, L., Hughes, M., Keavney, B., de la Pompa, J. L., Sled, J., Spielmann, N., Teboul, L., Zaffran, S., Mill, P., Liu, K. J.

(2024) , Dis Model Mech , 17 , dmm050913

10.1242/dmm.050913

PMC11603121

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