Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
Lack of transmission of murine norovirus to mice via in vitro fertilization, intracytoplasmic sperm injection, and ovary transplantation
Raspa, M., Mahabir, E., Fray, M., Volland, R., Scavizzi, F.
Inactivation of class II PI3K-C2alpha induces leptin resistance, age-dependent insulin resistance and obesity in male mice
Alliouachene, S., Bilanges, B., Chaussade, C., Pearce, W., Foukas, L. C., Scudamore, C. L., Moniz, L. S., Vanhaesebroeck, B.
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing
Nicod, J., Davies, R. W., Cai, N., Hassett, C., Goodstadt, L., Cosgrove, C., Yee, B. K., Lionikaite, V., McIntyre, R. E., Remme, C. A., Lodder, E. M., Gregory, J. S., Hough, T., Joynson, R., Phelps, H., Nell, B., Rowe, C., Wood, J., Walling, A., Bopp, N., Bhomra, A., Hernandez-Pliego, P., Callebert, J., Aspden, R. M., Talbot, N. P., Robbins, P. A., Harrison, M., Fray, M., Launay, J. M., Pinto, Y. M., Blizard, D. A., Bezzina, C. R., Adams, D. J., Franken, P., Weaver, T., Wells, S., Brown, S. D., Potter, P. K., Klenerman, P., Lionikas, A., Mott, R., Flint, J.
Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination
Warr, N., Siggers, P., Carre, G. A., Wells, S., Greenfield, A.
Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles
Elshorbagy, A. K., Jerneren, F., Scudamore, C. L., McMurray, F., Cater, H., Hough, T., Cox, R., Refsum, H.