Research supported by MLC

The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to beta-Cell Mitochondrial Dysfunction in Type 2 Diabetes

Peiris, H., Duffield, M. D., Fadista, J., Jessup, C. F., Kashmir, V., Genders, A. J., McGee, S. L., Martin, A. M., Saiedi, M., Morton, N., Carter, R., Cousin, M. A., Kokotos, A. C., Oskolkov, N., Volkov, P., Hough, T. A., Fisher, E. M., Tybulewicz, V. L., Busciglio, J., Coskun, P. E., Becker, A., Belichenko, P. V., Mobley, W. C., Ryan, M. T., Chan, J. Y., Laybutt, D. R., Coates, P. T., Yang, S., Ling, C., Groop, L., Pritchard, M. A., Keating, D. J.

(2016) , PLoS Genet , 12 , e1006033

10.1371/journal.pgen.1006033

Pmc4873152

View Full Paper


A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior

Ehrmann, I., Gazzara, M. R., Pagliarini, V., Dalgliesh, C., Kheirollahi-Chadegani, M., Xu, Y., Cesari, E., Danilenko, M., Maclennan, M., Lowdon, K., Vogel, T., Keskivali-Bond, P., Wells, S., Cater, H., Fort, P., Santibanez-Koref, M., Middei, S., Sette, C., Clowry, G. J., Barash, Y., Cunningham, M. O., Elliott, D. J.

(2016) , Cell Rep , 17 , 3269-3280

10.1016/j.celrep.2016.12.002

Pmc4873152

View Full Paper


A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse

Hood, D., Moxon, R., Purnell, T., Richter, C., Williams, D., Azar, A., Crompton, M., Wells, S., Fray, M., Brown, S. D., Cheeseman, M. T.

(2016) , Dis Model Mech , 9 , 69-79

10.1242/dmm.021659

Pmc4728332

View Full Paper


Transcription driven somatic DNA methylation within the imprinted Gnas cluster

Mehta, S., Williamson, C. M., Ball, S., Tibbit, C., Beechey, C., Fray, M., Peters, J.

(2015) , PLoS One , 10 , e0117378

10.1371/journal.pone.0117378

Pmc4319783

View Full Paper


The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity

Possamai, L. A., McPhail, M. J., Khamri, W., Wu, B., Concas, D., Harrison, M., Williams, R., Cox, R. D., Cox, I. J., Anstee, Q. M., Thursz, M. R.

(2015) , Liver Int , 35 , 764-73

10.1111/liv.12689

Pmc4319783

View Full Paper


1 19 20 21 22 23