Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model
Spiers, H., Hannon, E., Wells, S., Williams, B., Fernandes, C., Mill, J.
Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss
Carrott, L., Bowl, M. R., Aguilar, C., Johnson, S. L., Chessum, L., West, M., Morse, S., Dorning, J., Smart, E., Hardisty-Hughes, R., Ball, G., Parker, A., Barnard, A. R., MacLaren, R. E., Wells, S., Marcotti, W., Brown, S. D.
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to beta-Cell Mitochondrial Dysfunction in Type 2 Diabetes
Peiris, H., Duffield, M. D., Fadista, J., Jessup, C. F., Kashmir, V., Genders, A. J., McGee, S. L., Martin, A. M., Saiedi, M., Morton, N., Carter, R., Cousin, M. A., Kokotos, A. C., Oskolkov, N., Volkov, P., Hough, T. A., Fisher, E. M., Tybulewicz, V. L., Busciglio, J., Coskun, P. E., Becker, A., Belichenko, P. V., Mobley, W. C., Ryan, M. T., Chan, J. Y., Laybutt, D. R., Coates, P. T., Yang, S., Ling, C., Groop, L., Pritchard, M. A., Keating, D. J.
A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior
Ehrmann, I., Gazzara, M. R., Pagliarini, V., Dalgliesh, C., Kheirollahi-Chadegani, M., Xu, Y., Cesari, E., Danilenko, M., Maclennan, M., Lowdon, K., Vogel, T., Keskivali-Bond, P., Wells, S., Cater, H., Fort, P., Santibanez-Koref, M., Middei, S., Sette, C., Clowry, G. J., Barash, Y., Cunningham, M. O., Elliott, D. J.
A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse
Hood, D., Moxon, R., Purnell, T., Richter, C., Williams, D., Azar, A., Crompton, M., Wells, S., Fray, M., Brown, S. D., Cheeseman, M. T.