Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
Gonadal sex reversal at single-cell resolution in Znrf3-deficient mice
Kay, R. G. G., Reeves, R., Siggers, P., Greenaway, S., Mallon, A. M., Wells, S., Koo, B. K., Mayère, C., Nef, S., Greenfield, A., Simon, M. M.
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)
Vacca, M., Kamzolas, I., Harder, L. M., Oakley, F., Trautwein, C., Hatting, M., Ross, T., Bernardo, B., Oldenburger, A., Hjuler, S. T., Ksiazek, I., Lindén, D., Schuppan, D., Rodriguez-Cuenca, S., Tonini, M. M., Castañeda, T. R., Kannt, A., Rodrigues, C. M. P., Cockell, S., Govaere, O., Daly, A. K., Allison, M., Honnens de Lichtenberg, K., Kim, Y. O., Lindblom, A., Oldham, S., Andréasson, A. C., Schlerman, F., Marioneaux, J., Sanyal, A., Afonso, M. B., Younes, R., Amano, Y., Friedman, S. L., Wang, S., Bhattacharya, D., Simon, E., Paradis, V., Burt, A., Grypari, I. M., Davies, S., Driessen, A., Yashiro, H., Pors, S., Worm Andersen, M., Feigh, M., Yunis, C., Bedossa, P., Stewart, M., Cater, H. L., Wells, S., Schattenberg, J. M., Anstee, Q. M., Tiniakos, D., Perfield, J. W., Petsalaki, E., Davidsen, P., Vidal-Puig, A.
TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system
Akula, S. K., Marciano, J. H., Lim, Y., Exposito-Alonso, D., Hylton, N. K., Hwang, G. H., Neil, J. E., Dominado, N., Bunton-Stasyshyn, R. K., Song, J. H. T., Talukdar, M., Schmid, A., Teboul, L., Mo, A., Shin, T., Finander, B., Beck, S. G., Yeh, R. C., Otani, A., Qian, X., DeGennaro, E. M., Alkuraya, F. S., Maddirevula, S., Cascino, G. D., Giannini, C., Burrage, L. C., Rosenfield, J. A., Ketkar, S., Clark, G. D., Bacino, C., Lewis, R. A., Segal, R. A., Bazan, J. F., Smith, K. A., Golden, J. A., Cho, G., Walsh, C. A.
Tissue specific differences in the assembly of mitochondrial complex I is revealed by a novel ENU mutation in ECSIT
Nicol, T. Falcone, S. Blease, A. Vikhe, P. Civiletto, G. Omairi, S. S. Viscomi, C. Patel, K. Potter, P. K.
The parenting hub of the hypothalamus is a focus of imprinted gene action
Higgs, M. J., Webberley, A. E., Allan, A. J., Talat, M., John, R. M., Isles, A. R.