Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
TissUExM enables quantitative ultrastructural analysis in whole vertebrate embryos by expansion microscopy
Steib, E., Tetley, R., Laine, R.F., Norris, D.P., Mao, Y., Vermot, J.
Tissue Proteome of 2-Hydroxyacyl-CoA Lyase Deficient Mice Reveals Peroxisome Proliferation and Activation of ω-Oxidation
Khalil, Y., Carrino, S., Lin, F., Ferlin, A., Lad, H. V., Mazzacuva, F., Falcone, S., Rivers, N., Banks, G., Concas, D., Aguilar, C., Haynes, A. R., Blease, A., Nicol, T., Al-Shawi, R., Heywood, W., Potter, P., Mills, K., Gale, D. P., Clayton, P. T.
Shift work-like patterns effect on female and male mouse behavior
Banks, G., Nolan, P.M., Bourbia, N.
Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing
Newton, S., Kong, F., Carlton, A. J., Aguilar, C., Parker, A., Codner, G. F., Teboul, L., Wells, S., Brown, S. D. M., Marcotti, W., Bowl, M. R.
Mendelian gene identification through mouse embryo viability screening
Cacheiro, P., Westerberg, C. H., Mager, J., Dickinson, M. E., Nutter, L. M. J., Muñoz-Fuentes, V., Hsu, C. W., Van den Veyver, I. B., Flenniken, A. M., McKerlie, C., Murray, S. A., Teboul, L., Heaney, J. D., Lloyd, K. C. K., Lanoue, L., Braun, R. E., White, J. K., Creighton, A. K., Laurin, V., Guo, R., Qu, D., Wells, S., Cleak, J., Bunton-Stasyshyn, R., Stewart, M., Harrisson, J., Mason, J., Haseli Mashhadi, H., Parkinson, H., Mallon, A. M., Smedley, D.