Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis
Wu, Y., Bai, Y., McEwan, D. G., Bentley, L., Aravani, D., Cox, R. D.
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring
Gaspar, R. S., Unsworth, A. J., Al-Dibouni, A., Bye, A. P., Sage, T., Stewart, M., Wells, S., Cox, R. D., Gibbins, J. M., Sellayah, D., C, E. Hughes
Loss of O-GlcNAcase catalytic activity leads to defects in mouse embryogenesis
Muha, V., Authier, F., Szoke-Kovacs, Z., Johnson, S., Gallagher, J., McNeilly, A., McCrimmon, R. J., Teboul, L., van Aalten, D. M. F.
Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo
Laber, S., Forcisi, S., Bentley, L., Petzold, J., Moritz, F., Smirnov, K. S., Al Sadat, L., Williamson, I., Strobel, S., Agnew, T., Sengupta, S., Nicol, T., Grallert, H., Heier, M., Honecker, J., Mianne, J., Teboul, L., Dumbell, R., Long, H., Simon, M., Lindgren, C., Bickmore, W. A., Hauner, H., Schmitt-Kopplin, P., Claussnitzer, M., Cox, R. D.
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of down syndrome-related phenotypes
Lana-Elola, E., Cater, H., Watson-Scales, S., Greenaway, S., Müller-Winkler, J., Gibbins, D., Nemes, M., Slender, A., Hough, T., Keskivali-Bond, P., Scudamore, C. L., Herbert, E., Banks, G. T., Mobbs, H., Canonica, T., Tosh, J., Noy, S., Llorian, M., Nolan, P. M., Griffin, J. L., Good, M., Simon, M., Mallon, A. M., Wells, S., Fisher, E. M. C., Tybulewicz, V. L. J.